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Takeda Pharmaceuticals Global Program Leader, Neuroscience in Boston, Massachusetts

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Job Description

The Global Program Leader is a seasoned leader fully dedicated, responsible and accountable for overarching Global Program(s). The GPL defines the asset strategy and leads all development and LCM projects associated with an asset from discovery to the marketplace. The guiding frame is defined by Takeda values of Patient-Trust-Reputation-Business.

  • GPLs must be experienced, versatile and strong enterprise leaders

  • Committed to simultaneously driving regulatory approval as well as launch and global patient access

  • Ability to partner with all functions to drive, deliver and maximize asset value

  • Effective in communicating, decision making and committing to areas of joint decision making

This is best achieved by a unique fit for purpose combination of skills reflected in these critical skill categories. Additional information in the Knowledge and Skills section.

  • Inspirational Leadership

  • Strategic Vision

  • Strong Analytical Credibility

  • Execution Skills

  • Stakeholder Relationship

  • For a given asset, responsible for an overarching global program strategy and execution. The GPL leads all research, development, commercial and LCM activities associated with an asset from discovery to the marketplace with full accountability. It may involve conventional molecules or novel modalities such as Cell Therapy or Gene Therapy, large scale programs through to launch and beyond, or smaller scale programs (e.g. rare disease or early development programs).

  • Leads the Asset Strategy together with the commercial leader in the context of unmet medical need, competitive landscape, and key TPP attributes required to bring the product to market and to ensure global access for patients in context of Takeda’s values: Patient-Trust-Reputation-Business. This must take into consideration all development and commercial requirements as well as potential local/regional key requirements

  • For a given asset, the GPL is the single leader of a cross functional team, the Global Program Team (GPT). The GPL ensures through the functional sub-teams leaders and their teams all project deliverables achieve defined project scope & objectives, budget and timelines with full functional support, keeping in mind value maximization and strong sense of the time/quality balance.

  • Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables of the functional sub-teams for a given asset. GPT members are directly accountable to the GPL on the sub-team objectives.

  • Accountable with the responsible Global Program Manager for activities operating budgets within the global program; leads budget setting in collaboration with functions and manages variance to budget ensuring overall Takeda financial objectives are met.

  • Reports on program progress, issues, related updates, new requests for decision related to strategic scope or budget increase (new recommendations, change or buy-up) or timelines change and risks to TA Unit or and Takeda executive management governance committees as per company process.

  • Manages several assets, depending on the size and stage or the programs

  • Showcases the GPL leadership skills and Enterprise GPT operating model functioning and deliverables through all job attributes defined at Takeda

  • May lead key business initiatives: Evaluates new opportunities and provides overall support for feasibility studies on potential global programs.

  • Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively to the GPL community


Program Strategy, Activity Planning and Execution

  • Leads the Global Program in setting program vision, strategy, goals, priorities and long-term plans and schedules. Aligns cross-functional, cross-divisional project goals with Takeda business needs and strategies.

  • Works closely with the GPM in order to provide strategic, process, and operational leadership to multiple GPTs and Takeda functions in the successful delivery of projects from discovery to commercialization and LCM activities. Could manage 3-5 projects for across all phases of development including innovative early POM/POC in novel mechanisms with less-defined regulatory pathways through large-scale Phase III/submission projects and global launch projects.

  • Links GPT cross-functional sub-teams, such as the Clinical Subteam, Commercial Subteam, Pharmaceutical Sciences (CMC) Subteam, etc. to the GPT through function-based subteam leaders to execute according to the Enterprise GPT Playbook, align and ensure transparency of all program-related activities.

  • Provides leadership and support to TA Leaders and Sub-team leaders to set the vision and direction for the Therapeutic Area and prioritizes all aspects of projects within a global program.

  • Reports on progress of projects, plans/plan changes, critical path, possible scenario and issues/risks/impact to TA Unit and Takeda executive management through internal or external reviews of global programs.

  • Leads key business initiatives: for example, evaluates new opportunities (i.e.: in-licensing candidates, impact of change in market conditions or availability of new project data in disease areas where Takeda has little or no previous experience) and provides overall support for feasibility studies on potential global programs-non exhaustive list

Fiscal Responsibility

  • Accountable with the responsible GPM for project operating budgets within the global program; monitor and control expenditures; manages variance between budgeted and actual expenditures of time, dollars, and personnel while meeting overall Takeda financial objectives.

Resource and Issue Management

  • Manages internal and external resources (people, information, technologies, time, and capital); allocates project resources appropriately, given division, function and individual goals and objectives to align with business imperatives.

  • Proactively and regularly identifies/monitor project risks before they transform into issues and develops contingency plans; communicates timely and proactively project-related issues to senior executive management and manages issues to resolution.

  • Consults with TAU, Franchise Leadership and Portfolio Office to deliver accurate and timely project status and deliverable information to enable the organization to focus on key priorities and enhance its ability to deliver work (e.g., studies/projects) on-time and on-budget (including proficient use of systems to improve reporting or access to data).

Change Management

  • Proactively responds to the dynamics of a changing marketplace; directs adjustments in functional or cross-divisional plans in response to changes in strategic direction. Change management agent for the GPT.

  • Contributes to the creation and maintenance of systems/databases for the purpose of tracking key performance indicators (KPIs), trending, learning, and improving decisions regarding program performance and continuance.

Matrix Team Management

  • Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables or functional sub-teams within individual projects. Sub-team leads are primarily accountable to the GPL. Stakeholder management is also an expectation as a result of the highly matrixed work environment.



  • Advanced scientific degree (MD, or PhD, or PharmD) or MBA

  • Minimum of 10 years related experience in the pharmaceutical industry, with working knowledge of research and development and commercial operations

  • Minimum 8 years interdisciplinary global experience with complex projects including strategy and execution and matrix team management

  • Late stage clinical development and submission experience


  • Advanced degree in science or business is desired

  • Broad business/enterprise orientation is highly preferred

Knowledge and Skills:

  • Passionate about developing others into future leaders


  • Willingness to travel to various meetings or client sites, including overnight trips. Some international travel may be required.

  • Requires approximately 25-50% travel.

This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy

Base Salary Range: $195,000.00 to $278,000.00, based on candidate professional experience level. Employees may also be eligible for Short-Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program, and Paid Volunteer Time Off.


  • 401(k) with company match and Annual Retirement Contribution Plan

  • Tuition reimbursement Company match of charitable contributions

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Boston, MA

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Full time