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Job Description

Objective / Purpose:

As Director of the Biophysical Characterization team, lead and strategically guide a team, developing and implementing analytical methods and strategies, ensuring high quality and speedy data generation to support biologics discovery and production, and driving innovation in characterization and development.

Accountabilities:

• _Leadership and Team Management:  _

• Lead and inspire a team of scientists in the application of mass spectrometry and biophysical techniques

• Develop and mentor team members, fostering a culture of innovation and collaboration

• Manage budgets, resources, and timelines effectively

• _Strategic Planning and Method Development:  _

• Develop and implement forward-thinking mass spectrometry and biophysical strategies for biologics development 

• Stay abreast of the latest advancements in these fields

• Design and execute experiments to characterize biologics, including protein structure, stability, and purity

• Develop and validate analytical methods for use in product characterization and quality control

• _Collaboration and Communication:  _

• Partner with cross-functional teams (e.g., research, development, manufacturing) to support product development

• Ensure sequences correctness before CMC stable cell line development

• Communicate scientific findings and recommendations clearly and concisely

• Liaise with external partners (e.g., CROs, CMOs) as needed 

• _Regulatory Compliance:  _

• Prepare and review analytical reports for IND filing 

• Problem Solving and Innovation:   

• Investigate and resolve analytical challenges and issues

• Identify opportunities for process improvement and innovation

Education & Competencies (Technical and Behavioral)

• Education: PhD in biochemistry, biophysics, chemistry, or a related field

• Experience: 10+ years of experience in the biotechnology or pharmaceutical industry, with a strong track record of leadership and success

• Technical Expertise:   

• Extensive knowledge of mass spectrometry techniques (e.g., LC-MS, Peptide mapping) and developability method development

• Experience with biophysical techniques (e.g., SEC, CD, HIC, DSF/DSC, IEX)

• Solid understanding of analytical method development and validation

• Experience with protein characterization and quality control, formulation screening

• Knowledge of cGMP and regulatory requirements

• Skills:   

• Strong leadership, communication, and interpersonal skills

• Ability to work effectively in a team environment

• Excellent problem-solving and analytical skills

• Proficiency in data analysis and interpretation 

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$169,400.00 - $266,200.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.