Massachusetts Creative Jobs

MassHire Job Quest Logo

Job Information

Alexion Pharmaceuticals Associate Director, Global Program Manager in Boston, Massachusetts

Some opportunities happen only once in a lifetime - like a job where you have the chance to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients.

This is what you will do:

The Associate Director, Global Program Manager (GPM) is responsible for partnering on the strategic and operational, planning, and decision-making processes within Alexion’s Global Program Teams. This role serves as the strategic partner and operational leader (Global Program Manager) for the development/lifecycle programs and provides program management excellence to the Global Program Teams (GPT).

The Associate Director GPM works closely with the Global Program Team Leader (GPTL) who is responsible for overall team leadership to ensure robust and balanced cross-functional planning, decision-making, implementation, monitoring, and reporting for one or multiple related programs to ensure strong alignment between Development/ Lifecycle strategy (if applicable) and operational execution by the GPT. The GPM works to ensure the cross-functional teams operate effectively with positive team dynamics and adhere to Alexion’s operating model. Based on organizational and SPPM needs, the AD GPM may also partner with senior level program management leaders on asset-level teams and/or corporate initiatives.

The Associate Director GPM must be able to both provide strategic vision and guide the team to develop integrated plans for successfully executing the strategy. The Associate Director GPM will provide content expertise on the timing, costs and resources required for development plans on these potential programs and work with the GPT to mitigate risks. The successful delivery of development milestones and goals ties to the overall longevity of Alexion’s pipeline and commercial infrastructure.

The Associated Director GPM will be responsible for one or more programs with complex cross-functional and/or cross-program strategic implications in Alexion’s pipeline/lifecycle portfolio.

You will be responsible for:

  • Provide Strategic and operational support to the GPTL to ‘pressure-test’ program team’s assumptions, drive scenario planning / trade off analysis and integrate cross functional planning across development into the overall program plan

  • Work closely with the GPTL to facilitate the elaboration, approval, and execution of the global program strategy, as well as facilitate decision-making process for their program(s). In close collaboration with GPT members drives evaluation of product opportunities/ scenarios and develops comprehensive integrated recommendations (eg, to Governance Committees) resulting in strategic and operational product plans.

  • Coordinate development process planning activities of the GPT including Milestone setting, Strategic Integrated Development Plans, Long Range Plan, budget inputs and go/no go criteria as appropriate.

  • Manage and forecast an integrated program budget and resource plan, including assumptions, investment buy-ups/buy-downs, in partnership with the GPTL, Finance team member, and the GPT. Ensures transparency and understanding of the approved plan, funding status of activities, and identifies potential efficiencies with the team.

  • Responsible for Planning & Control (P&C) engagements within the Global Program Team

  • Prepare and manage governance interactions in partnership with the GPTL and ensures timely input of program status/risks/issues into the reporting system for high quality portfolio reporting.

  • Work independently to provide best in class operations and program management expertise to drive GPT members towards excellence in execution eg.

  • Define and track scope, risks, budget/costs and time, critical path

  • Maintain the overall development plans and enterprise portfolio inputs

  • Drive team meetings/agendas/minutes/action items including decision and action logs

  • Facilitate team goal setting and tracking to ensure adherence to plan and strategy, and end of year team evaluation process

  • Coordinate GPT communications to ensure team member alignment

  • Manage set up of sub-teams and provide guidance on sub-team management

  • Drive Stage Gate Review preparation for “holistic program views” at program inflection points

  • Responsible for scheduling meetings, preparing agenda, and coordinating pre-read materials with input from team members, facilitating meetings that focus on clear decisions and actions, and writing minutes

  • Develops and maintains timelines for programs (within the enterprise management system, i.e. PlanIT) aligned with corporate goals ensuring that adequate progress and milestones are met and that deviations and risks are communicated

  • Demonstrates compliance on time-reporting by adhering to MYTIME requirements.

  • Manages program communication tools in order to provide up-to-date program information and documentation to R&D leadership

  • Responsible for key stakeholder management and communications with Therapeutic Area Leads (including SPPM TA Lead).

  • Reinforce team operating principles to maximize alignment within the team and with others

  • Participate incross-functional initiatives (either strategic and/or operational) if required by SPPM

  • Proactively address opportunities for improvement within SPPM and support the growth and professional maturity of the SPPM organization

  • Represent the SPPM vision and mission to the Alexion organization and be a spokesperson for SPPM

  • The Associate Director GPM may manage or provide guidance/mentorship to other junior staff as needed

    % of Time

    Job Function and Description


    GPT Program Management


    Program Management Processes and Operating Model


    Supervision/Mentoring of Junior SPPM Staff (if applicable)

    You will need to have:

  • Minimum BS degree with 10+ years of industry experience, or advance degree with 6+ years of industry experience

  • 6-10+ years of experience within one or more functional role(s) in pharmaceutical R&D drug development, biotechnology drug development, or related industry.

  • At least 4 years of cross-functional program management experience in complex development programs

  • Independent creative thinker and enabler requiring minimum oversight. A self-starter who is pro-active, motivates, and has tact, diplomacy, is a true team player, with excellent leadership skills

  • Demonstrated ability to provide effective program management leadership in terms of setting program plans for the lifecycle of a program from discovery through launch

  • Proven track record of planning and managing complex programs in different phases of development including cross functional deliverables (Research, CMC and Commercial)

  • Solid understanding of the processes in drug development/market access in biologics/small molecules etc. relating to required development plans, task durations, cost, and product value assessment

  • Strong influencing and interpersonal skills including negotiation, managing meetings and group dynamics, ability to balance concerns of line management with objectives of cross-functional team.

  • Ability to operate and motivate a team in a matrix environment and ability to work with / influence people at all levels in the organization without authority

  • Must be well organized and have strong attention to detail while maintaining the end-to-end cross functional view

  • Technical proficiency includes demonstrated proficiency in the use of program planning and resource forecasting tools and systems (e.g., Microsoft Project or equivalent, resource forecasting, decision analytics, simulation), and the use of reporting tools

  • Expertise in budget and resource management and prioritization frameworks

  • Demonstrated understanding of program risk management and mitigation in order to simulate the likely obstacles to program progression

  • Strong organizational skills and the ability to deal with competing priorities; high level of problem-solving capability and business acumen, ability to balance competing priorities and quickly and objectively drive the team towards a path which maximizes value

  • Excellent communication skills (written and verbal communication skills in English)

  • Highly skilled in negotiation, facilitation, and managing matrix team dynamics

  • Experience with business development activities preferred. i.e., diligence, integration, scenario planning

  • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

    We would prefer for you to have:

  • Project Management Institute (PMI) qualifications or similar formal training preferred



    Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: .

    Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants. All US-based employees must comply with Alexion's COVID-19 vaccination mandate. Alexion provides exceptions based on applicable state law as well as reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding a legally required exemption or accommodation, please contact Alexion participates in E-Verify.

    As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, and much more.

    AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click here ( .